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    TB-500 Peptide: What Practices Should Know About Identity and Sourcing

    Short answer: In PubChem, TB-500 is the synthetic acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH (Ac-LKKTETQ), with molecular formula C38H68N10O14 and a molecular weight of about 889 g/mol (PubChem CID 62707662). The LKKTETQ sequence is a short stretch found within the naturally occurring protein thymosin beta-4 (gene TMSB4X) (UniProt P62328). So TB-500 isn't full-length thymosin beta-4. It's a synthetic fragment based on part of that protein. Clinics receive it as a lyophilized vial, and Biomed Peptides supplies it only to verified licensed providers.

    There's a lot of loose language about this compound online. Many sources use "TB-500" and "thymosin beta-4" as if they meant the same thing. This guide sticks to the verifiable identity facts, the supply format, and how provider access works.

    What is the TB-500 peptide?

    Chemical identity

    PubChem lists TB-500 (also written TB500 or TB 500) under CID 62707662 with these properties (PubChem):

    Attribute Value
    Common names TB-500, TB500, TB 500
    Sequence Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
    Length 7 amino acids, N-terminally acetylated
    Molecular formula C38H68N10O14
    Molecular weight ≈889.0 g/mol
    CAS (as listed) 885340-08-9

    How TB-500 relates to thymosin beta-4

    Thymosin beta-4 is a small, naturally occurring human protein. UniProt's reference sequence (P62328, TMSB4X) contains the motif LKKTETQ (UniProt P62328), and TB-500's sequence matches that seven-residue stretch with an acetyl cap added. The accurate way to describe TB-500 is as a synthetic peptide corresponding to a short region of thymosin beta-4, not as the whole protein.

    This matters when you read a COA. Mass spectrometry for TB-500 should come out near 889 Da, not near the mass of full-length thymosin beta-4. If a supplier's paperwork mixes the two up, ask why before you order.

    How TB-500 is supplied to clinics

    Lyophilized vial format

    TB-500 comes as a freeze-dried powder in a sealed vial. Lyophilized material is much more stable than peptide in solution, which is why it's the standard format for shipping and storage (Bachem). Our lyophilized peptides guide explains the format and the reconstitution workflow for clinic staff.

    The Biomed Peptides lyophilized catalog lists TB500 in 5 mg and 10 mg vials. The catalog also lists a separate Wolverine Blend product (5/5 mg and 10/10 mg). Check its composition in the provider portal before ordering, because blends should be verified from their own COA.

    Storage and diluent

    • Keep vials sealed, cold, dry, and away from light, and follow the label first (Bachem).
    • Let a cold vial reach room temperature before you open it.
    • Limit freeze-thaw cycles.
    • Reconstitute only with the diluent named on the labeling. Our article on bacteriostatic water for peptides explains one common option.

    The lyophilized peptides storage guide covers each storage rule in detail.

    TB-500 peptide: where to buy as a provider

    Searches like "TB-500 peptide buy" or "TB-500 peptide where to buy" mostly turn up consumer-facing sites. For a medical practice, the question that matters is whether a supplier will verify your license and give you lot documentation.

    Biomed Peptides supplies physician-use product only to licensed healthcare providers and GPOs. We don't sell to patients or consumers. Here's the process:

    1. Apply through the provider application.
    2. Verification of your license and clinic details, usually within 24–48 hours.
    3. Portal access to the catalog, wholesale pricing, and quality documentation.
    4. Fulfillment for office use or patient-specific orders, with shipping to all 50 states.

    Prescribing authority depends on the license and the state. Our overview of who can prescribe peptides covers the general framework. Confirm your own state's rules, since we don't give legal advice.

    Documentation to request for TB-500

    Before you add TB-500 to your formulary, ask any supplier for:

    • A lot-specific COA showing identity by mass spectrometry (≈889 Da), purity by HPLC, and peptide content
    • An endotoxin report
    • Labeled storage conditions and expiration dating
    • Separate documentation for any blend containing TB-500

    Our guide to choosing a wholesale peptide supplier explains how to read and compare this paperwork. For background on compounding channels, see what a 503A pharmacy is.

    Source TB-500 for your practice

    Licensed practices can apply for provider access to see TB-500 pricing and lot documentation, or browse the lyophilized catalog.

    FAQ

    What is the TB-500 peptide?

    TB-500 is the synthetic acetylated heptapeptide Ac-LKKTETQ (C38H68N10O14, about 889 g/mol). Its sequence corresponds to a short region of the human protein thymosin beta-4.

    Is TB-500 the same as thymosin beta-4?

    No. Thymosin beta-4 is a small protein whose UniProt reference sequence is 44 amino acids long. TB-500 is a seven-residue synthetic peptide matching one stretch of that sequence.

    How is TB-500 supplied?

    As a lyophilized powder in a sealed vial, reconstituted with the diluent named on the labeling.

    Where can a practice buy TB-500 peptide?

    From a provider-only supplier that verifies licensure and gives you lot COAs. Biomed Peptides supplies TB-500 to approved providers through /apply.

    Can consumers buy TB-500 from Biomed Peptides?

    No. All orders go through licensed healthcare providers or GPOs.

    What should a TB-500 COA show?

    Identity by mass spectrometry at about 889 Da, HPLC purity, peptide content, and the lot number, along with a separate endotoxin report.

    Sources

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