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    DSIP Peptide: A Provider's Guide to Identity, Vial Format, and Access

    Short answer: The DSIP peptide is a nine-amino-acid peptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE). Schoenenberger and Monnier isolated it from rabbits and reported the sequence in 1977 (Schoenenberger & Monnier, 1977). Its nonproprietary name is emideltide. PubChem lists it as CID 68816, molecular formula C35H48N10O15, molecular weight ≈848.8 g/mol, CAS 62568-57-4 (PubChem). For clinics, Biomed Peptides supplies DSIP 5 mg and DSIP 10 mg as lyophilized powder in sealed vials, to verified licensed providers only.

    This guide covers what the compound is, where it appears on FDA's compounding pages, how it's supplied and stored, and how provider access works. Clinical decisions stay with the prescribing clinician.

    What is the DSIP peptide?

    Origin and name

    "DSIP" is short for delta sleep-inducing peptide, the name given in the original 1977 paper, which described isolating the nonapeptide from rabbits and synthesizing it (Schoenenberger & Monnier, 1977). The name is historical. It's a label from that early animal research, not a description of an approved clinical use.

    You'll see a few names on documentation:

    • Emideltide, the INN. PubChem lists "Emideltide [INN]" alongside DSIP and "delta sleep-inducing peptide" (PubChem)
    • Emideltide (DSIP), the form FDA uses on its compounding pages (FDA)
    • DSIP peptide or DSIP nonapeptide, common shorthand

    Sequence and structure

    WAGGDASGE (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu)

    Attribute Value
    Common names DSIP, delta sleep-inducing peptide
    Nonproprietary name Emideltide
    Length 9 amino acids
    Molecular formula C35H48N10O15
    Molecular weight ≈848.8 g/mol
    CAS (as listed in PubChem) 62568-57-4
    PubChem CID 68816

    It's a short, linear peptide with two acidic residues (Asp and Glu) and an N-terminal tryptophan. These identity values are what you check on a certificate of analysis (COA): the mass spectrometry result should match the ≈848.8 Da expected mass, and the sequence should match the nine residues above.

    Regulatory context: FDA's 503A pages

    Section 503A sets the rules for which bulk drug substances pharmacists and physicians may compound with. A substance generally has to have a USP or NF monograph, be a component of an FDA-approved drug, or appear on FDA's 503A bulks list. FDA also requires a valid COA and an FDA-registered (section 510) manufacturing establishment (FDA).

    Here's what FDA's own pages currently show for DSIP:

    • FDA's page on bulk drug substances that may present significant safety risks lists Emideltide (DSIP) under "Bulk drug substances nominated but withdrawn," which FDA describes as substances "previously in category 2 of the interim policies" whose nominations "were withdrawn by the nominators." The page summarizes the concerns FDA identified, and providers should read it directly. The content is marked current as of April 22, 2026 (FDA).
    • FDA's list of substances nominated under 503A (updated May 14, 2026) doesn't name emideltide or DSIP in category 1, 2, or 3 (FDA nominations list).

    These pages change often. Confirm current status with your compounding pharmacy before you make any formulary decision. For background, see what a 503A pharmacy is.

    How DSIP is supplied to clinics

    DSIP 5mg and 10 mg vials

    DSIP ships as a lyophilized (freeze-dried) powder in a sealed vial. The Biomed Peptides lyophilized catalog lists two strengths:

    • DSIP 5 mg
    • DSIP 10 mg

    People search "dsip 5mg" because 5 mg is a common vial strength. Vial strength is the amount of peptide in the sealed vial. It doesn't change the molecule. Make sure the vial label, the COA, and your records all show the same strength. Our lyophilized peptides guide explains the format and the clinic workflow.

    Storage on receipt

    • Keep vials sealed, dry, and protected from light. Follow the product label first.
    • Manufacturer guidance says peptides shouldn't be stored in solution because they "may slowly undergo chemical degradation." For longer storage, Bachem recommends keeping them as a lyophilizate in a tightly closed container below −15 °C, with lower temperatures preferred, and allows 4 °C for short-term use (Bachem).
    • Peptides tend to be hygroscopic. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder (Bachem).
    • Bachem notes that peptides containing Trp have limited shelf lives and that Trp-containing peptides "require special care to avoid oxidation." DSIP starts with tryptophan (W), so follow the labeled expiration and storage conditions closely.

    Our lyophilized peptides storage guide covers each step in detail. For the diluent, see bacteriostatic water for peptides.

    Documentation to request

    Ask for these with every DSIP lot:

    • Lot-specific COA with an identity result (typically mass spectrometry matching ≈848.8 Da), HPLC purity, and peptide content where reported
    • Endotoxin results where applicable
    • Manufacturer and site information, since 503A requires a section 510-registered establishment for bulk drug substances (FDA)
    • Labeled storage conditions and expiration

    Our peptide COA and third-party testing guide explains how to read each section of a COA and match it to the vial in hand.

    DSIP peptide buy: how provider access works

    Many results for "dsip peptide buy" are consumer storefronts. Biomed Peptides works differently. We supply physician-use product only to licensed healthcare providers, and we don't sell to patients or consumers. Wholesale pricing is visible only to approved accounts.

    1. Submit the provider application.
    2. Our team verifies your credentials, usually within 24–48 hours.
    3. Approved accounts can view pricing, the full lyophilized catalog, and lot documentation.
    4. Order for office use or patient-specific fulfillment, with shipping to all 50 states.

    Source DSIP for your practice

    Licensed practices and med spas can apply for provider access to view DSIP 5 mg and DSIP 10 mg pricing and COAs, or browse the lyophilized catalog to plan their formulary.

    FAQ

    What is the DSIP peptide?

    DSIP is a nine-amino-acid peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, first isolated from rabbits and sequenced in 1977. PubChem lists its molecular weight as about 848.8 g/mol (CID 68816).

    Is emideltide the same as DSIP?

    Yes. Emideltide is the INN for DSIP. PubChem lists them as synonyms, and FDA uses "Emideltide (DSIP)."

    What is DSIP's status on FDA's 503A pages?

    FDA's significant-safety-risks page (current as of April 22, 2026) lists Emideltide (DSIP) among substances previously in category 2 whose nominations were withdrawn. FDA's May 14, 2026 nominations list does not name it in categories 1–3. Confirm current status with your compounding pharmacy.

    Does Biomed Peptides carry DSIP 5mg?

    Yes. The catalog lists DSIP 5 mg and DSIP 10 mg lyophilized vials.

    Where can a practice buy DSIP?

    From a provider-only supplier that verifies licensure. Biomed Peptides supplies DSIP to approved providers. Apply at /apply to see pricing and documentation.

    Sources

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