CJC-1295 Peptide: A Provider's Guide to Identity, No DAC Listings, and Sourcing
Short answer: "CJC-1295" is used in catalogs for two related but chemically distinct tetrasubstituted analogues of human growth hormone–releasing hormone fragment 1–29 (hGRF(1–29)). The form originally identified as CJC-1295 carries a C-terminal lysine with a maleimidopropionyl Drug Affinity Complex (DAC) group (Jetté et al., 2005; PubChem CID 91971820, ≈3647.2 g/mol). CJC-1295 No DAC (also called Mod GRF 1-29) is the same 29-residue substituted backbone without that albumin-binding handle (PubChem CID 56841945, ≈3367.9 g/mol). Biomed Peptides lists CJC-1295 NO DAC for licensed providers as a lyophilized vial.
This guide sticks to identity, how No DAC appears in our catalog, supply format, and how provider access works. Clinical decisions stay with the prescribing clinician.
What is the CJC-1295 peptide?
Shared backbone
Both forms are built on a 29-residue amide analogue of the N-terminal fragment of human GHRH / GRF. Relative to native hGRF(1–29), the shared core carries four substitutions that were designed to improve proteolytic stability: D-Ala at position 2, Gln at 8, Ala at 15, and Leu at 27 (Jetté et al., 2005).
Three-letter sequence of that shared core (C-terminal amide):
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
CJC-1295 with DAC vs CJC-1295 No DAC
| Attribute | With DAC (historic CJC-1295) | No DAC (Mod GRF 1-29) |
|---|---|---|
| Structure | 29-residue core + Lys with Nε-3-maleimidopropionyl group | 29-residue substituted core only |
| Molecular formula (PubChem) | C165H269N47O46 | C152H252N44O42 |
| Molecular weight (PubChem) | ≈3647.2 g/mol | ≈3367.9 g/mol |
| PubChem | CID 91971820 | CID 56841945 |
| CAS (as resolved in PubChem) | 446262-90-4 | 863288-34-0 |
The ≈280 Da mass difference is how mass spectrometry separates the two on a lot COA. Treat them as different products with different documentation.
Jetté and colleagues described CJC-1295 as "a tetrasubstituted form of hGRF(1–29) with an added Nε-3-maleimidopropionamide derivative of lysine at the C terminus" (Jetté et al., 2005). Catalog language that says No DAC means the maleimide-lysine handle is absent.
How CJC-1295 No DAC is listed for clinics
The Biomed Peptides lyophilized catalog lists:
- CJC-1295 NO DAC, 10 mg vial
- CJC-1295 NO DAC + IPAMORELIN blend vials at 5/5 mg and 10/10 mg
Ipamorelin is a separate pentapeptide. See our ipamorelin peptide guide for its identity and standalone vials. A blend listing does not change the fact that each peptide needs its own identity confirmation on the lot documentation.
Pricing appears only after a provider account is approved.
How CJC-1295 No DAC is supplied
Lyophilized vial format
CJC-1295 No DAC ships as a lyophilized powder in a sealed vial. Freeze-drying removes most of the water that drives peptide degradation, so dry vials hold up better in storage and transit than solutions (Bachem). Our lyophilized peptides guide covers the format and clinic reconstitution workflow.
Storage and diluent
- Store sealed, cold, dry, and away from light, following the label (Bachem).
- Let a cold vial warm to room temperature before opening.
- Avoid repeated freeze-thaw cycles.
- Use only the diluent named on the labeling.
CJC-1295 peptide buy: how providers get access
Searches like "cjc 1295 peptide buy" mostly lead to consumer storefronts. Biomed Peptides supplies physician-use product only to licensed healthcare providers and GPOs. We don't sell to patients or consumers.
- Submit the provider application.
- Our team verifies credentials, usually within 24–48 hours.
- Approved accounts can see wholesale pricing, the full catalog, and quality documentation.
- Order for office use or patient-specific fulfillment, with shipping to all 50 states.
Prescribing authority depends on license and state. See who can prescribe peptides. For sourcing channels, see what a 503A pharmacy is.
Documentation to request
- Lot-specific COA: MS identity matching ≈3367.9 Da for No DAC (not ≈3647 Da for the DAC form), HPLC purity, and peptide content
- Endotoxin report where applicable
- Labeled storage conditions and expiration
Our wholesale peptide supplier guide explains how to compare suppliers on documentation.
Source CJC-1295 No DAC for your practice
Licensed practices can apply for provider access to view CJC-1295 NO DAC pricing and lot documentation, or browse the lyophilized catalog.
FAQ
What is the CJC-1295 peptide?
CJC-1295 refers to tetrasubstituted hGRF(1–29) analogues. The historic DAC form includes a maleimidopropionyl-lysine handle (≈3647.2 g/mol). CJC-1295 No DAC is the 29-residue substituted core without that handle (≈3367.9 g/mol).
What does "No DAC" mean?
DAC means Drug Affinity Complex—the maleimide group designed for albumin binding. No DAC means that handle is not present on the molecule.
Is CJC-1295 No DAC the same as ipamorelin?
No. They are different peptides. Biomed Peptides also lists a CJC-1295 NO DAC + IPAMORELIN blend; each component still has its own identity.
Where can a practice buy CJC-1295 peptide?
From a provider-only supplier that verifies licensure. Biomed Peptides supplies CJC-1295 NO DAC to approved providers through /apply.
How is CJC-1295 No DAC supplied?
As a lyophilized powder in sealed vials. Our catalog lists a 10 mg standalone vial plus blend strengths.
Sources
- PubChem. Cjc 1295 (CID 91971820). https://pubchem.ncbi.nlm.nih.gov/compound/91971820
- PubChem. L-tyrosyl-D-alanyl-…-L-argininamide / CJC-1295-no DAC (CID 56841945). https://pubchem.ncbi.nlm.nih.gov/compound/56841945
- Jetté L, Léger R, Thibaudeau K, et al. Human growth hormone-releasing factor (hGRF)1–29-albumin bioconjugates… Identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052–3058. https://doi.org/10.1210/en.2004-1286
- Bachem. Handling and Storage Guidelines for Peptides. https://www.bachem.com/knowledge-center/handling-and-storage-guidelines-for-peptides/
